ACSS2 - Wikipedia
Acyl-coenzyme A synthetase short-chain family member 2 is an enzyme that in humans is encoded by the ACSS2 gene. [5][6] This gene encodes a cytosolic enzyme that catalyzes the …
ACSS2 Gene - GeneCards | ACSA Protein | ACSA Antibody
2024年12月24日 · ACSS2 (Acyl-CoA Synthetase Short Chain Family Member 2) is a Protein Coding gene. Diseases associated with ACSS2 include Orofacial Cleft 1 and Myasthenic …
Acetyl-CoA synthetase 2(ACSS2): a review with a focus on
2022年7月7日 · ACSS2-mediated regulation of acetylation is related to substance metabolism and tumorigenesis. In mammalian cells, ACSS2 utilizes intracellular acetate to synthesize acetyl …
ACSS2 and metabolic diseases: from lipid metabolism to …
2025年2月25日 · Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) is a nucleo-cytosolic enzyme with both lipogenic and metabolic regulatory roles. Studies on ACSS2 have …
ACSS2 gene variants determine kidney disease risk by controlling …
2023年12月5日 · In this study, we used kidney-specific expression of quantitative traits and single-nucleus open chromatin analysis to show that genetic variants linked to kidney …
ACSS2 towards memory-related processes, we examined whether this metabolic-epigenetic axis could be targeted in diseases characterized by memory loss, particularly Alzheimer’s disease …
ACSS2-dependent histone acetylation improves cognition in …
2023年7月12日 · Model depicts that ACSS2 expression is downregulated in the brains of 5×FAD model mice and AD patients. Of note, ACSS2 downregulation mediates a reduction in …
Acetyl-CoA synthetase 2 (ACSS2), an important member of the acetyl-CoA synthetase (ACSS) family, can catalyze the conversion of acetate to acetyl coenzyme A (acetyl-CoA). Currently, …
Targeting ACSS2 to Regulate HIF-2α Stability and Suppress ccRCC …
2024年10月15日 · Drs. Beckermann, Rathmell, and Bacigalupa discuss their recent research exploring the therapeutic potential of inhibiting ACSS2 to reduce HIF-2α levels, thereby …
ACSS2 upregulation enhances neuronal resilience to aging and …
2024年3月29日 · ACSS2 can be recruited to the nucleus and chromatin, locally supplying acetyl-CoA to directly fuel histone acetyltransferase enzymes and key neuronal gene expression. …