ACSL4 - Wikipedia
Long-chain-fatty-acid—CoA ligase 4 is an enzyme that in humans is encoded by the ACSL4 gene. [5] [6] [7] The protein encoded by this gene is an isozyme of the long-chain fatty-acid …
酰基辅酶A合酶ACSL4：铁死亡和脂肪酸代谢的重要靶标,Chinese …
2023年7月14日 · 摘要长链酰基辅酶 a (coa) 合酶 4 (acsl4) 是一种将 coa 酯化为特定多不饱和脂肪酸（如花生四烯酸和肾上腺酸）的酶。根据积累的证据，acsl4 催化的花生四烯酰辅酶 a 生物 …
ACSL4 Gene - GeneCards | ACSL4 Protein | ACSL4 Antibody
2024年12月24日 · ACSL4 (Acyl-CoA Synthetase Long Chain Family Member 4) is a Protein Coding gene. Diseases associated with ACSL4 include Intellectual Developmental Disorder, X …
Science子刊：靶向ACSL4，抑制铁死亡，防治铁死亡相关疾病_澎 …
该研究发现，as-252424是一种特异性和靶向性的acsl4抑制剂，具有显著的抗铁死亡功能，并揭示了其在调控铁死亡中的潜在作用和分子机制，为铁死亡相关疾病的治疗提供了一种潜在治疗方 …
文献解析|ACSL4调控细胞脂质组成，影响铁死亡敏感性
2024年12月10日 · ACSL4. ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. 铁死亡是一种由谷胱甘肽过氧化物酶4（GPX4）调控的细胞坏死形式。早期研究 …
The ACSL4 Network Regulates Cell Death and Autophagy in …
ACSL4 is an enzyme involved in the intracellular conversion of long-chain fatty acids and coenzyme A into fatty-acid coenzymes. It plays a vital role in various biological processes, …
Cell | 西湖大学揭示癌症转移新靶点：PUFA与铁死亡的“致命组合”
2024年12月13日 · acsl4缺失抑制了sk-hep-1-luc细胞的肺转移，但未显著改变体外增殖或皮下肿瘤生长，表明acsl4在肝癌中的促外渗作用具有普遍性。 此外，用ARA处理SK-HEP-1细胞显著 …
酰基辅酶 A 合成酶长链家族成员 4（ACSL4）基因 | MCE
关于 acsl4 Cytogenetic location: Xq23 Genomic coordinates (GRCh38): X:109,641,335-109,733,257 (from NCBI) This gene has 18 transcripts (splice variants), 271 orthologues, 12 …
ACSL4 as a Potential Target and Biomarker for Anticancer: From ...
2022年7月13日 · Recently, acyl-CoA synthetase long-chain family 4 (ACSL4) is found be participated in the activation of long chain fatty acids metabolism, immune signaling …
ACSL4 acyl-CoA synthetase long chain family member 4 [ (human)]
ACSL4 is not only a sensitive monitor of ferroptosis, but also an important contributor of ferroptosis. ACLS4 and ACLS3 have roles in insulin secretion; Silencing of ACSL4 eliminated …
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