2018年9月4日 · SLC1A5, known as ASCT2, is a neutral amino acid transporter belonging to the SLC1 family and localized in the plasma membrane of several body districts. ASCT2 is an …

2018年9月3日 · SLC1A5, known as ASCT2, is a neutral amino acid transporter belonging to the SLC1 family and localized in the plasma membrane of several body districts.

2019年12月10日 · In this study, ASCT2, an amino acid transporter responsible for glutamine transport, in addition to LAT1 and GLS, is overexpressed in HNSCC and associated with poor …

2018年10月15日 · ASCT2 (alanine-serine-cysteine transporter 2; SLC1A5), an Na +-dependent neutral amino acid transporter encoded by the SLC1A5 gene, is predominantly localized in the …

Keywords: ASCT2; SLC1A5; cancer; glutamine metabolism; glutamine transport.

2018年10月15日 · In conclusion, this review describes the function, regulatory mechanism, and inhibitors of ASCT2 in cancer, suggesting that high expression of ASCT2 is a promising …

2024年1月13日 · ASCT2(SLC1A5) is the main glutamine transporter in tumor (Fig. 1). It is regulated by multiple tumor associated transcription factors including Rb/E2F [ 15 ], androgen …