In the event of high heterogeneity, we conducted subgroup analyses stratified by individual members of the miR-34 family (miR-34a, miR-34b, and miR-34c) to explore potential sources of variability.
为探究 miR-34a-5p 在多囊卵巢综合征(PCOS)中的作用,研究发现其可调节 Notch 信号通路影响颗粒细胞功能,为治疗提供新靶点。 多囊卵巢综合征(Polycystic Ovary Syndrome,PCOS)是一种让许多青春期和育龄女性烦恼不已的代谢内分泌疾病。全球范围内,大约 6% - 21% 的 ...
UFC and Bellator veteran Frank Mir’s comeback with the GFL has been put on hold. That’s because early Monday morning, Mir revealed on Instagram that he recently “underwent an emergency spinal fusion ...
Frank Mir’s proposed Global Fight League debut is likely in jeopardy after he recently underwent emergency spinal surgery. Advertisement The Ultimate Fighting Championship and Bellator MMA ...
Mufti Shah Mir was close to the Jamiat Ulema-e-Islam-F (JUI-F). He previously survived two attempts on his life. The attack came days after two leaders of JUI-F were shot dead in Khuzdar.
Mufti Shah Mir, Muslim scholar who helped Pakistan's ISI in abducting Kulbhushan Jadhav from Iran, shot dead by unknown men. Mufti Shah Mir was killed by unknown gunmen in Balochistan. Mir was ...
本文通过对脊髓性肌萎缩症(SMA)小鼠模型研究,揭示 miR-34a 在疾病中的关键作用及机制。 脊髓性肌萎缩症(SMA)研究背景 脊髓性肌萎缩症(SMA)是一种严重的神经退行性疾病,由生存运动神经元 1(SMN1)基因突变所致。该疾病会引发脊髓前角 α - 运动神经元 ...
The aim of this study was to generate miRNA sponges and tough decoys to target miR-34 in the mouse heart. We present data to show that using both approaches we were unable to get significant knockdown ...
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