This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...

The investigational treatment comprises autologous CD34-positive hematopoietic stem cells (HSCs) that are collected from patients and modified ex vivo with EXG-001, an RNA-based Sendai virus vector ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

In these experiments, ESCs were observed for 72 h after RA addition. The fraction of Zscan4+ cells is defined as the ratio of A Zscan4+ with the total area occupied by cells. In symbol, The profile of ...