GO enrichment analysis of PDE1A-interacting genes showed that PDE1A might interact with YTHDF2 and participate in m6A-containing RNA binding. The binding between PDE1A and YTHDF2 was verified, and ...

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Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. m 6 A RNA modification has been linked to ...

跨修饰交互：研究乳酸化与乙酰化、m6A甲基化的协同调控，例如乳酸化通过促进YTHDF2表达影响m6A修饰的致癌机制。 · 采用抗乳酸化抗体结合高分辨质谱，实现万级修饰位点的精准鉴定。 · 开发乳酸化动态成像探针，活体监测肿瘤或脑组织中的乳酸化水平变化。

该研究发现，YTHDF2在B细胞恶性肿瘤中呈现异常高表达，并通过双重机制促进癌细胞的生存与免疫逃逸。 该研究展示了YTHDF2如何通过识别m6A和m5C修饰 ...

该研究发现，YTHDF2在B细胞恶性肿瘤中呈现异常高表达，并通过双重机制促进癌细胞的生存与免疫逃逸。 该研究展示了YTHDF2如何通过识别m6A和m5C修饰 ...

Results and Discussion: We validated 13 proteins that interact with p72, including CD63, B2M, YTHDF2, FTH1, SHFL, CDK5RAP3, VIM, PELO, TIMP2, PHYH, C1QC, CMAS, and ERCC1. Enrichment analysis and ...

N6-Methyladenosine (m6A) affects the fate of modified RNA molecules and is involved in tumor progression. Different webservers were used in our research to investigate the mRNA transcription and ...