Mindrank Ltd. has announced that the FDA has cleared the company’s IND application for MRANK-106, a potentially first-in-class, orally available dual inhibitor of WEE1 and YES1 kinases, for the ...

Zhangming Niu, Founder and CEO of MindRank. “By simultaneously targeting WEE1 and YES1 kinases, MRANK-106 has demonstrated remarkable preclinical efficacy in multiple hard-to-treat cancers with ...

The FDA cleared the investigational new drug application for MRANK-106, a dual WEE1/YES1 kinase inhibitor, targeting advanced solid tumors. The FDA has cleared the investigational new drug (IND) ...

Google's former HR chief wrote that he'd "never seen a large scale, systematic approach like this." While such lists aren't illegal, they are unusual, other employment and HR experts told BI.

CHK1 also phosphorylates and activates WEE1 during G2 (centriole maturation), which can phosphorylate and inhibit CDK1 activity. CDK1/Cyclin B interacts with Aurora kinase A to enhance its ...

Chad Brooks,Managing Editor Business.com earns commissions from some listed providers. Editorial Guidelines. To help you choose the best HR software for your business, we spent countless hours ...

MicroRNAs (miR), as important epigenetic control factors, reportedly regulate wound repair. However, our insufficient knowledge of clinically relevant miRs hinders their potential therapeutic use. For ...

Editorial Guidelines. If managing your human resources (HR) functions in-house becomes too much to handle, you can outsource some or all of these services. Human resources outsourcing (HRO ...

Single-cell analysis is pivotal to deciphering complex phenomena like heterogeneity, bistability, and asynchronous oscillations, where a population ensemble cannot represent individual behaviors. Bulk ...