E1s and E2s first work generically across the cell to activate and prepare ubiquitin for attachment. E3 ligases then ensure that the tag is added to the right protein; as such, hundreds of specific ...

One of the first things that students learn when they enter a biology class is the central dogma: DNA → RNA → ...

Our interdisciplinary school is leading scientific exploration and engineering expertise in sustainability solutions, biomedical innovation and advanced materials. We address crucial issues like ...

Product safety, measuring the health effects of exposure to chemicals and chemical contaminants in food.

Defects in ubiquitin–UBD interactions are relevant for development of disease, such as inflammation and cancer. The new structure-based insights provide strategies for the design of new ...

Figure 1: Domain structure of ubiquitin-specific proteases ... Isopeptide versus peptide cleavage. The chemical features of an isopeptide bond differ significantly from those of a peptide bond.

You are free to share (copy and redistribute) this article in any medium or format and to adapt (remix, transform, and build upon) the material for any purpose, even commercially within the parameters ...

Chemical engineers are problem solvers - they bring new medicines to market, develop alternative fuels, keep food manufacturing safe, and create new manufacturing materials. They move small-scale ...

Department of Chemical and Systems Biology, Stanford Cancer Institute, School of Medicine Stanford University, Stanford, California 94305-6104, United States Department of Chemical and Systems Biology ...

Summary: Entrepreneurs often grapple with the decision of whether to structure their business as a Company or a Limited Liability Partnership (LLP). Both offer the advantage of limited liability and ...

Professor Robert Mokaya, Chair of the Inclusion and Diversity Committee and President Elect of the Royal Society of Chemistry, shares his views on what the future of our inclusion and diversity ...

With global companies seeking to de-risk their supply chains, which are dependent on China, the chemical sector in India has the opportunity for a significant growth. * The Dahej PCPIR project in ...