综上所述,在生长因子受体激活条件下,ERK与USP9X共同参与了肝癌细胞中TK1表达的调控,通过同时增强其代谢与非代谢功能促进肿瘤的增殖。这一发现强调了TK1作为癌症治疗的潜在分子靶点,对靶向代谢酶的抗癌药物的研发具有重要的指导意义。
A recent study from Northwestern University has uncovered a genetic factor that may play a key role in autism. Researchers found that a specific gene affects how brain cells form connections during ...
Rapid activation of adenosine monophosphate-activated protein kinase (AMPK) induces phosphorylation of mitochondrial-associated proteins, a process by which phosphate groups are added to regulate ...
Non-small cell lung cancer (NSCLC) constitutes a significant proportion of lung cancer cases, and despite advancements in treatment modalities, radiotherapy resistance remains a substantial hurdle in ...