Macrophage-to-myofibroblast transition (MMT) contributes to CaOx-induced fibrosis in nephrocalcinosis. EZH2 is the critical regulator that promotes kidney fibrosis by meditating MMT via the DUSP23 ...

Boehringer Ingelheim has cemented the potential of its idiopathic pulmonary fibrosis (IPF) drug with a second phase 3 win in a related lung disease leading the drugmaker to expand the indications ...

The SOX9 gene locus is not only extensive but also intricate, and it could promote fibrosis in different organs or tissues, including cardiac fibrosis, liver fibrosis, kidney fibrosis, pulmonary ...

or excessive dynamic airway collapse of the posterior tracheal wall), vocal cord paresis or paralysis, obstructive granuloma, and/or associated sub-stenosis. The chest CT scan looked for other ...

Prognosis of patients with cystic fibrosis (CF) varies extensively despite recent advances in targeted therapies that improve CF transmembrane conductance regulator (CFTR) function. Despite being a ...