The Traitors star Nikki Garcia, also known as Nikki Bella in WWE, dated 16-time world champion John Cena from 2012-2018. At WrestleMania 33, Cena proposed to Garcia in front of the live audience ...
You can now listen to the Cypriot entry for the 69th Eurovision Song Contest - 'Shh' will be performed by Theo Evan. On Tuesday 11 March, the Cyprus Broadcasting Corporation (CyBC) unveiled the ...
Liquid–liquid Phase Separation (LLPS) of proteins and nucleic acids has emerged as a new paradigm in the study of cellular activities. It drives the formation of liquid-like condensates containing ...
We thank Professor John L. Rubenstein for his comments, suggestions, and edits. We are grateful to Professor Hua Han for sharing the Rbpj floxed mice, and Professor Jean M. Hebert for sharing ...
There are three ligands present in vertebrates which may activate the Hh signaling pathway: Sonic hedgehog (Shh), Indian hedgehog (Ihh), and Desert hedgehog (Dhh). In normal tissues, Dhh is primarily ...
Obesity poses a significant risk of developing type II diabetes and other diseases. Hedgehog (Hh) signaling has been shown to inhibit adipose tissue development, but its effect on diet-induced obesity ...
Early loss of T-box3 disrupts limb initiation, causing limb defects that phenocopy Sonic Hedgehog (Shh) mutants. Later ablation of T-box3 in posterior limb mesenchyme causes digit loss. In contrast, ...
A protein called fibroblast growth factor (FGF) serves as the activator, and a gene variant dubbed Sonic hedgehog (Shh) acts as an inhibitor. When the researchers increased or decreased the activity ...