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胆固醇激活交感神经促进毛发生长,为脱发治疗带来新希望
胆固醇通过蛋白激酶 A(PKA)磷酸化酪氨酸羟化酶激活交感神经:研究发现,酪氨酸羟化酶(TH)在 Ser40 位点的磷酸化对其活性影响重大,HA - 1004 作为 PKA 抑制剂可抑制 TH 在 Ser40 位点的磷酸化。实验表明,注射 HA - 1004 抑制交感神经活性后,胆固醇促进毛发生长 ...
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