为提升人造肉产量，研究人员优化细胞源与组织过程，发现 MSTN 敲除可增强 MYOD1 介导的人造肉生产，意义重大。 随着全球人口的持续增长，对蛋白质的需求也在不断攀升，牛肉作为备受欢迎的蛋白质来源，其消费量预计在未来十年还会继续增长。然而，传统的 ...

Nicotinic acetylcholine receptors (nAChRs) are widely expressed in a variety of cell types and are involved in multiple physiological regulatory mechanisms in cells, tissues and systems. Increasing ...

Correspondence to Dr David G DeNardo, Medicine, Washington University, St. Louis, MO 63132, USA; ddenardo{at}wustl.edu Results In KPC mice, the expression levels of phosphorylated STAT3 (pSTAT3) were ...

We demonstrate that the SGS mutations in SKI abolish interaction with PSMAD2 and PSMAD3 and this results in an inability of SKI to be degraded in response to TGF-β/Activin signaling. We go on to show ...

Cell surface receptors are central to the cell's ability to generate coordinated responses to the multitude of biochemical and physical cues in the microenvironment. However, the mechanisms by which ...