CAPE CANAVERAL, Fla. — Stuck in space no more, NASA astronauts Butch Wilmore and Suni Williams returned to Earth on Tuesday, ...

这表明HDCA可能通过影响胆汁酸的吸收和运输来调节脂代谢。 脂肪组织中脂代谢相关基因和蛋白表达的变化 在脂肪组织中，HDCA抑制了乙酰辅酶A羧化酶（ACC）和过氧化物酶体增殖物激活受体γ（PPARG）的基因表达，上调了激素敏感性脂肪酶（HSL）的基因表达（P0.05）。

To address this, researchers developed uPEn, integrating a ubiquitin variant (i53) to enhance genome stability and repair efficiency. The study applied uPEn to insert a consensus Kozak sequence into ...

此外，还利用双荧光素酶报告实验，精准验证 miR-130a 与靶基因 PPARG 的直接结合关系。 下面来看具体的研究结果： LNP@miR-130a 的设计与特性：研究人员巧妙地将姜来源的纳米颗粒超声破碎，与修饰后的抗受体共同孵育形成磷脂双层，再通过微流控处理将 miR-130a ...

Results: We identified 74 genes associated with ferroptosis in pediatric sepsis. Among them, five key genes (MAPK3, MAPK8, PPARG, PTEN, and STAT3) were confirmed through PPI network analysis and ...

Moreover, the metabolite-butyric acid may be involved. FIGURE 1. Protein-metabolite network construction. A full network based on the primary protein, PPARG (orange node), associated metabolites (blue ...

To activate Hh signaling in the adipose tissue specifically in postnatal mice, we wished to use the Pparg-tTA allele to target the adipocyte lineage following withdrawal of doxycycline (Dox) from the ...