b: MINDTY1 increases its stability and avoids degradation by removing the ubiquitin chain from YAP. c: ECM stiffness increases the nuclear localization of YAP by activating the integrin-FAK-CDC42-PP1A ...

The emergence and rapid spread of SARS-CoV-2, the pathogen of COVID-19, have caused a worldwide public health crisis. The SARS-CoV-2 main protease (Mpro) is an essential enzyme for the virus and ...