In conclusion, by identifying PEBP1 as an amplifier of mitochondrial stress signals, our study provides new insights into cytoplasmic mechanisms which ensure appropriate responses to acute ...
In mice, a ketogenic diet remodeled the translatome of pancreatic cancer cells, rendering them vulnerable to targeted therapy ...
Gpr54 deletion lowers NFATC3 and SFRP1 levels, activates the Wnt/β-catenin pathway, which stimulates DPCs and HFSCs, and ...
During your time with Pathways to Medicine, you will participate in events and activities throughout Year 12 and 13. Every aspect of the programme is designed to help you make a strong and informed ...
Phosphorylation is the enzymatic process through which a phosphate group is added via an ester bond, generally by a kinase, to either a small molecule or a protein. Protein phosphorylation is ...
Mitochondrial DNA (mtDNA)-encoded RNA molecules undergo extensive processing to generate mature RNA, including removal of ...
Kigali, Rwanda – November 13, 2024 – Today, the Government of Rwanda and the World Bank launched the Rwanda Country Economic Memorandum (CEM), titled “Pathways to Sustainable and Inclusive Growth in ...
A new report from the Los Angeles Regional Consortium (LARC) and the Career Ladders Project (CLP) details one initiative to building and scaling dual-enrollment pathways and the elements of a ...
Key Laboratory of Advanced Energy Materials Chemistry, Ministry of Education State Key Laboratory of Advanced Chemical Power Sources Collaborative Innovation Center of Chemical Science and Engineering ...
This analysis uncovered venetoclax resistance mechanisms and pointed towards potential alternative treatments targeting the resistance-associated molecular pathways. For instance, high levels of ...
More information: Jiyoen Kim et al, TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse model, Nature Neuroscience (2024). DOI: 10.1038/s41593-024-01777-2 ...