These molecules, upregulated in cancer cells, are excreted through a surprising mechanism—lysosomal exocytosis. Researchers published their results in the Journal of Cell Biology on January 3 ...

Background: The lysosome plays a vitally crucial role in tumor development and is a major participant in the cell death process, involving aberrant functional and structural changes. However, there ...

These molecules, upregulated in cancer cells, are excreted through a surprising mechanism—lysosomal exocytosis. Even more fascinating is the intricate relationship between lysosomal exocytosis ...

School of Environment and Civil Engineering, Dongguan University of Technology, Dongguan 523808, P. R. China Guangdong Key Laboratory of Nanomedicine, CAS-HK Joint Lab of Biomaterials, CAS Key ...

The 5xFAD model of Alzheimer’s disease is a double transgenic PS1/APP mouse that harbors five human mutations associated with familial AD (line Tg6799): the Swedish (K670N/M671L), Florida (I716V), and ...