研究人员探究 TRFD 治疗原发性骨质疏松的效果，发现其经 MAPK/HIF-1 α 通路促骨抑脂，有治疗潜力。 在骨骼健康领域，骨质疏松（Osteoporosis，OP）是一个日益严峻的问题。它就像隐藏在身体里的 “沉默杀手”，悄无声息地侵蚀着人们的骨骼。骨质疏松以低骨量和骨 ...

这篇研究揭示了炎症性疼痛和性腺激素对大鼠芬太尼自我给药的性别特异性影响，为防治阿片类药物滥用提供新视角。 一、研究背景 在美国，超半数成年人受疼痛困扰，阿片类药物虽常用于止痛，却极易被滥用，缓解疼痛是阿片类药物滥用最主要的自我报告 ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

“物理智能(Physical AI)”，黄仁勋在CES 2025上发表主题演讲时提出的新概念。他指出，即将全面到来的“Physical AI”时代，将是在1000万工厂、20万仓库、15亿汽车和卡车及海量人形机器人之上应用的下一波万亿规模市场驱动力。 “物理智能(Physical AI)”，是黄仁勋在 ...

Yi Mai Jian herbal formula (YMJ) is formulated with Eucommiae Folium, Astragali Radix, Ligustri Lucidi Fructus, and Elaeagnus Fructus to improve bone function in traditional Chinese medicine. The anti ...

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Emerging evidence supports that osteogenic differentiation of skeletal progenitors is a key determinant of overall bone formation and bone mass. Despite extensive studies showing the function of ...

Osteoporosis is a common systemic bone disease caused by the imbalance between osteogenic activity and osteoclastic activity. Aged women are at higher risk of osteoporosis, partly because of estrogen ...