The ABCB1 transporter gene The 2677(T) variant of the ABCB1 gene holds promise as a biomarker for adjusting dosing for olanzapine and clozapine. The DRD3 (Ser9Gly) polymorphism, could prove useful ...

This manuscript describes important findings on a rhizobial effector, its cleavage, and legume receptors involved in symbiosis. The evidence supporting the main claims is solid, though some ...

The ability of the atypical antipsychotic drug candidate olanzapine to antagonize dopamine, serotonin, alpha-adrenergic and muscarinic receptors in vivo was assessed by various neurochemical ...

TEV’749 is a long-acting formulation of olanzapine, one of the most widely used atypical antipsychotic schizophrenia treatments to date. The drug was first approved in the 1990s and is currently ...

Research Center for Environmental Quality Management, Graduate School of Engineering, Kyoto University, Otsu, Shiga 520-0811, Japan Key Laboratory of Industrial Ecology and Environmental Engineering ...

Epidermal growth factor receptor (EGFR) is expressed in 50% of NSCLCs, and its expression is correlated with poor prognosis. These two factors make EGFR and its family members prime candidates for ...

The introduction of a new psychopharmaceutical medication instead of the previous one always poses a certain challenge. In the case of antipsychotics (AP), these problems are considerably more ...

Figure 1. Signal transduction mechanism of EGFR (epidermal growth factor receptor) transactivation by angiotensin II (AngII) in vascular smooth muscle cells leading to vascular remodeling. Please note ...