This important study characterizes and validates a new activity marker - fast labelling of engram neurons (FLEN) - which is transiently active and driven by cFos, allowing the monitoring of intrinsic ...

This study demonstrates the critical role of Afadin on the generation and maintenance of complex cellular layers in the mouse retina. The data are solid, which provides important insights into how ...

A patient has been in remission from neuroblastoma, a type of nerve cell cancer, for 18 years following treatment with chimeric antigen receptor (CAR) T cell therapy without requiring any additional ...

This may represent the longest reported remission in a patient with cancer treated with CAR-T cell therapy to date, the authors suggest. The findings are based on follow-up from a phase 1 clinical ...

Facial nerve paralysis describes weakness in the muscles on one or both sides of your face that causes an inability to smile, blink, or control other facial movements. It happens when the facial nerve ...

However, the precise mechanism of such CNS-related toxicities remains elusive. Methods: The effect of entrectinib-induced nerve cell damage was evaluated by the nerve cells (PC12, HT22 and SK-N-SH) ...

However, most animal cells have complex morphologies because the membrane adheres strongly to the cytoskeleton. In animal cells, movement of membrane into an endocytic vesicle or lamellipodium ...

"To counteract neurodegeneration, we need two things—stop neuron death and restore function of surviving neurons," said co-corresponding author Marco Capogrosso, Ph.D., assistant professor of ...