NQO1 = NADPH dehydrogenase quinone 1; SNP = single nucleotide polymorphism; TP53I3 = tumour protein p53 inducible protein 3. p53 lies at the hub of a vast signalling network. Polymorphisms in ...

State Key Laboratory of Natural and Biomimetic Drugs, Chemical Biology Center and School of Pharmaceutical Sciences, Peking University, No. 38, Xueyuan Rd, Beijing 100191, China ...

With economic growth and improved living standards, the incidence of diabetes has significantly increased, and the age of onset has gradually decreased, thus extending the overall course of diabetes.

NADPH: Nicotinamide adenine dinucleotide phosphate-diaphorase, NQO1: NADPH quinone reductase 1, ROS: Reactive oxygen species, TrxR: Thioredoxin reductase). Multiple clinical as well as translational ...

Neutrophils are armed with both oxidant-dependent and -independent pathways for killing pathogens. Activation of the phagocyte nicotinamide adenine dinucleotide phosphate (NADPH) oxidase constitutes ...