这表明 miR-99a 在白血病发生发展过程中扮演着重要角色，靶向 miR-99a 或 NIPBL 可能为血液恶性肿瘤的治疗开辟新途径。 总的来说，这项研究揭示了 miR-99a 在调控 HSPCs 中的关键作用，为理解正常和恶性造血过程提供了新的视角，也为未来开发针对血液疾病 ...

This important study investigates the function of a critical regulator of human early cardiac development. The convincing examination of GATA6 function is thorough and well-executed. The study will be ...

Accordingly, SA proteins interact with RNA, and R-loops, even in the absence of cohesin. Our results place SA1 on chromatin upstream of the cohesin ring and reveal a role for SA1 in cohesin loading ...