In the PNS, one Schwann cell forms a single myelin sheath (Figure 1A). By contrast, in the CNS, the oligodendrocyte sends cell processes to myelinate multiple segments on many axons (Figure 2).

Myelin is an insulating layer of lipids and proteins surrounding nerves. Myelin damage can cause problems with the nerves’ ability to send and receive electrical messages. Inflammatory disorders ...

and how myelin damage in either the peripheral or central nervous systems can be repaired. Myelin – produced by Schwann cells in the periphery and oligodendrocytes in the CNS – is defective in ...

Guillain-Barré Syndrome is a rare neurological disorder where the body’s immune system—which normally protects it from ...

More specifically, the myelin sheath — an insulating layer ... The condition can get progressively worse. Thus the peripheral nerves — the nerves that branch out from the brain and the spinal ...

It also involves autoantibodies (immune cells) that mistakenly attack the myelin sheath of peripheral nerves. Medications and therapies for CIDP focus on modifying immune responses to halt or slow ...

Guillain-Barré Syndrome occurs when the body’s immune system mistakenly attacks nerve cells, disrupting communication between ...

Inflammation in the brain, spinal cord, or peripheral nerves can damage myelin. Inflammation can develop as part of the body’s response to infection. In the case of MS and other autoimmune ...

The PMP22 gene codes for Peripheral Myelin Protein 22, a protein that is part of the myelin sheath—the protective cover—of peripheral nerves. That myelin sheath degrades in CMT1A. Because the ...