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增强髓鞘生成可挽救 PWMI 小鼠认知障碍:LIN28A 的关键作用
综合研究结论和讨论部分,此次研究揭示了 RNA 结合蛋白 LIN28A 在调节大脑髓鞘生成过程中起着至关重要的作用,其在 OPCs 中的表达降低与 PWMI 中的髓鞘生成受阻和认知功能受损相关。补充 LIN28A 能够挽救 PWMI ...
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