Alzheimer’s disease (AD) is often recognized by its well-known symptoms—memory loss, confusion, and cognitive decline. But ...

Alzheimer’s disease is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like changes in sleep, anxiety and depression can be early signs of the disease.

Alzheimer's Disease (AD) is characterized by a host of recognizable cognitive symptoms, but many non-cognitive symptoms like ...

Recently, the research team led by Professor Zhang Zhongtao and Professor Yao Hongwei from the General Surgery Center at ...

A cholesterol receptor protein called LDLR appears to be a key driver of neurotoxicity in sporadic ALS, per new research ...

LDL is often called “bad” cholesterol because when it accumulates in the blood, it can form plaque in the arteries, a ...

在结论与讨论部分，此次研究首次在沙特女性 MetS 患者中鉴定出 LDLR 基因外显子 4 的变异，并评估了其对蛋白结构和功能的影响。研究发现的变异可能是 MetS 发生或其并发症出现的潜在预测指标。不过，LDLR 基因突变与 MetS 之间的因果关系仍有待进一步明确。这一研究成果意义重大，为后续开展大规模人群筛查项目提供了重要依据，有助于制定针对心血管疾病的一级和二级预防措施，为沙特女性 ...

▎药明康德内容团队编辑（来源：武汉大学）中国心血管疾病患者超过3亿，其死亡人数占据总死亡人数的近50%。低密度脂蛋白（LDL）胆固醇是诱发心血管疾病的主要风险因素，统计发现每增加1mg/dL的LDL胆固醇，冠心病的发病率增加大约1%， ...

Herein, we reported that the use of crizotinib, a ROS1 inhibitor, exerted favorable survival benefit (exceeded 29 months) in a resectable stage IIIA NSCLC patient with novel LDLR–ROS1 fusion. A ...

12 mothers diagnosed as non-carriers after Sanger sequencing were selected for the reanalysis through TNGS. Genomic DNA was isolated from peripheral blood leukocytes and saliva and stored in the ...

Mechanisms have been controversial but recent evidence suggests that caveolar transcytosis across endothelial cells is the dominant pathway. Receptors involved are LDLR (LDL receptor), SR-B1 ...