研究人员为探究主动脉瘤（AA）向主动脉夹层（AD）进展机制，分析相关 RNA，发现 circ_0000006/miR-483-5p/KDM2B 轴，为防治提供新 ...

Patient 1 is a 5-year-and 9-month-old female, who initially presented to the outpatient clinic of the Catholic University of Korea, Eunpyeong St. Mary’s Hospital at 4 years and 10 months, due to ...

Vertebrate embryos achieve developmental competency during zygotic genome activation (ZGA) by establishing chromatin states that silence yet poise developmental genes for subsequent lineage-specific ...

How CGIs function mechanistically as nucleation sites for polycomb repressive complexes remains unknown. Here we discover that KDM2B (FBXL10) specifically recognizes non-methylated DNA in CGIs and ...