图3-1：重组LSD1 / KDM1A(Cat: # 31826) 蛋白纯度检测。 重组 LSD1 / KDM1A蛋白凝胶，8% SDS-PAGE考马斯亮蓝染色，MW：110kDa，纯度：＞90% 图3-2：重组LSD1 / KDM1A(Cat: # 31826) 活性检测。 重组 LSD1 / KDM1A蛋白活性测定：在含有 50 mM Tris-HCl pH 8.0 和 50 nM FAD ...

这篇文章利用ATAC-seq和RNA-seq关联分析揭示了与衰老和成熟过程中的染色质重塑和TFs重分布特征，发现了先锋因子AP-1在其中的关键作用。 本研究通过 ...

Acute Myeloid Leukemia (AML) is a type of cancer of the blood system that is characterized by an accumulation of immature hematopoietic cells in the bone marrow and blood. Its pathogenesis is ...

that targets lysine-specific demethylase 1 (LSD1 or KDM1A), an enzyme crucial for cancer stem and progenitor cells, particularly in abnormal bone marrow cells. Bomedemstat is currently being ...

This month's cover highlights the article Natural variations of adolescent neurogenesis and anxiety predict the hierarchical status of adult inbred mice by Nicolas Toni, Thomas Larrieu and colleagues.

Skeletal muscle exhibits remarkable plasticity in response to environmental cues, with stress-dependent effects on the fast-twitch and slow-twitch fibers. Although stress-induced gene expression ...

Meiosis is the basis of sexual reproduction. In female mammals, meiosis of oocytes starts before birth and sustains at the dictyate stage of meiotic prophase I before gonadotropins-induced ovulation ...

Human cytomegalovirus (HCMV) is a highly prevalent pathogen that induces life-long infections notably through the establishment of latency in hematopoietic stem cells (HSC). Bouts of reactivation are ...