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ATF4:肥胖诱导肝病中肝脏调节性 T 细胞功能的关键调控因子
为探究肥胖时肝脏调节性 T 细胞(T regs )功能及转录调控机制,研究发现 ATF4 介导其功能特化,为相关疾病治疗提供靶点。 在生命科学的免疫学领域,肥胖与肝脏疾病的关联一直是研究的热点。随着人们生活水平的提高,肥胖问题日益严重,肥胖引发的肝脏 ...
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