As mentioned above, while most adult HSCs in the bone marrow are quiescent, which divide only once every 2–5 months, HSCs in the fetus are in cell cycle, which allows them to expand during the ...

为探究 m6A 调节剂在肝癌（HCC）中的作用，研究人员发现 IGF2BP3 促进 HCC 进展，为其诊疗提供新方向。 肝癌（liver hepatocellular carcinoma，HCC）是一种常见且致命的肿瘤，中国的肝癌患者占全球病例的 50%。尽管近年来治疗手段有所进步，但疗效仍不理想。N6 - 甲基 ...

Following injury, many organs are capable of rapid regeneration of necrotic tissue to regain normal function. In contrast, the damaged heart typically replaces tissue with a collagen-rich scar, due to ...

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. This work is licensed under a Creative Commons ...

Department of Obstetrics and Gynecology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China ...

This valuable study combines massively parallel reporter assays and regression analysis to identify sequence features in untranslated regions contributing to the stability of in vitro transcribed mRNA ...

This collection highlights the most downloaded* Nature Communications papers in life and biological sciences published in 2024. Featuring authors from around the world, these papers highlight ...

The research aims to identify key molecular and mutational events in thyroid, adrenal and other endocrine tumors, and their clinical applications in endocrine pathology and molecular pathology for ...

Background: N6-methyladenosine (m6A), the most abundant chemical modification on eukaryotic messenger RNA (mRNA), is modulated by three class of regulators namely “writers,” “erasers,” and “readers.” ...