克隆:clone A2-10 (IgG2a), F10-21 (IgG2a), D8-6 (IgG2a), D1-2G (IgG2b), and D2-112 (IgG2b),识别不同种属来源II型胶原的保守区,溶解于PBS缓冲液中。 0天:小鼠尾静脉或腹腔注射5mg 克隆合剂。 3天:小鼠腹腔注射25-50ug LPS 注意:3-4天可诱发关节炎,7-10天达高峰期。10-14天可免疫LPS ...
The study by Pudlowski et al. shows that a previously-identified protein complex, composed of delta- and epsilon-tubulin together with TEDC1 and TEDC2, functions in generating centriolar triplet ...
在免疫学研究中,抗体亚型的功能解析是揭示疾病机制、开发靶向疗法的重要突破口。大鼠作为模式动物,其免疫系统与人类高度保守,而卵清蛋白(Ovalbumin, OVA)作为经典的食物过敏原和免疫调节靶点,常被用于研究I型超敏反应及黏膜免疫耐受。在这一背景下 ...
Skeletal muscle exhibits remarkable plasticity in response to environmental cues, with stress-dependent effects on the fast-twitch and slow-twitch fibers. Although stress-induced gene expression ...
The thymus is home to a significant number of resident B cells which possess several unique characteristics regarding their origin, phenotype and function. Evidence shows that they originate both from ...