New therapeutic "cocktails" could offer long-lasting relief for treatment-resistant asthma and other inflammatory diseases of ...

1 Department of Oncology, Harbin Medical University Cancer Hospital, Harbin, China 2 Department of Gastroenterology and Hepatology, Tianjin Second People’s Hospital, Tianjin, China The cancer-immunity ...

The problematic molecules—ICOSL, OX40L, and CD30L—keep memory T cells in the lungs on high alert. While typically these T cells are beneficial, preserving information about past infections to ...

The cocktails inhibit key molecules (called ICOSL, OX40L, and CD30L) that they found allow specialized tissue-resident memory T cells to stay active and maintained in high numbers in tissues.

Despite antigen affinity of B cells varying from cell to cell, functional analyses of antigen-reactive B cells on individual B cells are missing due to technical difficulties. Especially in the field ...