3月4日，国际学术期刊Cell Research在线发表了中国科学院分子细胞科学卓越创新中心童明汉组、复旦大学蓝斐团队和北京大学汤富酬团队的最新研究成果：“SETD1B-Mediated Broad H3K4me3 Controls Proper ...

The maintenance of CHG methylation is mediated by the CMT3-H3K9me2 pathway. CMT3 binds to two H3K9me2 proteins simultaneously and methylates DNA at nearby CHG sites. The methylated CHG DNA recruits Su ...

The diploid-to-haploid life form transition is governed by the loss of H3K9me2 and DNA demethylation of transposon-associated cis-regulatory elements. This event is associated with dramatic changes in ...

Among them, we identified the nearby Wnt7b gene as a direct Lnc-Rewind target. We show that Lnc-Rewind interacts with the G9a histone lysine methyltransferase and mediates the in cis repression of ...