Structure-based drug design is the design and optimization of a chemical structure with the goal of identifying a compound suitable for clinical testing — a drug candidate. It is based on ...

China: A recent prospective cohort study has revealed that obesity significantly reduces the effectiveness of febuxostat-based urate-lowering therapy (ULT) in male patients with primary gout, ...

Astronomers have discovered what may be the largest-scale structure in the known universe — a group of galaxy clusters and clusters of galaxy clusters that spans roughly 1.3 billion light-years ...

Objective: The study focuses on comparing the efficacy of a low-dose combination of febuxostat and benzbromarone versus each drug used alone for the treatment of gout. Methods: A prospective, ...