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揭秘 DET1 调控转录因子泛素化的分子机制,解锁细胞命运密码
为探究 DET1 - DDB1 - DDA1(DDD)复合物的作用机制,奥塔哥大学研究人员开展研究,揭示其结构及 E2 酶和 COP1 的招募机制,为理解相关细胞过程提供依据。 在生命的微观世界里,蛋白质的 “命运” 时刻受到各种精密机制的调控。其中,蛋白质的泛素化修饰(一种 ...
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