CDK1/Cyclin B interacts with Aurora kinase A to enhance its phosphorylation and activation of PLK1. Aurora kinase A activity is inhibited by BRCA1. PLK1 induces CDC25C activation and WEE1 degradation ...

Regulated hydrolysis of the phosphoinositide phosphatidylinositol(4,5)-bis-phosphate to diacylglycerol and inositol-1,4,5-P 3 defines a major eukaryotic pathway for translation of extracellular cues ...

Meiosis is a specialized cell cycle that requires sequential changes to the cell division machinery to facilitate changing functions. To define the mechanisms that ...

Different studies have shown that p30 also influences cell cycle progression. The G2/M checkpoint is regulated by a tight balance of phosphorylation and dephosphorylation events, where Cdc25c plays a ...

Wintering Monarch butterflies (Danaus plexippus), Santa Cruz, California. Masses of migrants gather in eucalyptus groves to overwinter before returning north; their numbers have decreased as a ...