Next, pre-washed and resuspended GMP ActiveMax ® Human T cell Activation/Expansion CD3/CD28 Beads (ACROBiosystems, Cat. No. GMP-MBS001) were added to the well at a 1:1 ratio. These were then ...

The work addresses the role of translation initiation in the early induction of specific genes during T cell activation. It primarily uses the Jurkat T cell line and demonstrates that the translation ...

This study uses a wide range of approaches to identify acylation as a key regulator of Orai1 channel activation and calcium entry. The results show a novel role for Orai1 acylation in promoting ...

Anti-CD3/CD28 treatment activated all classes of lymphocytes either directly (T cells) or indirectly (B and NK cells) but reduced monocyte numbers. Activated T and NK cells expressed senescence and ...

To stimulate CD8 + T-cell subsets with cytokines, cells were stimulated for 3 days with anti-CD3/CD28 Abs in the presence or absence of IL-2 (20 IU/mL), IL-15 (5 ng/mL; PeproTech, Rocky Hill, NJ, USA) ...