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For bloodstream infections caused by chromosomal AmpC β-lactamase-producing strains, cefepime may be an appropriate carbapenem-sparing treatment option. Cefepime is supported as an alternative to ...

The emergence of resistant to carbapenems Gram-negative bacteria (CR GNB) has severely challenged antimicrobial therapy. Many CR GNB isolates are only susceptible to polymyxins; however ...

The former wide spectrum “magic bullet,” imipenem, has been ousted by the emergence of carbapenem resistant (CR) pathogens. In endemic areas, infections with CR-bacteria occur in vulnerable patients, ...