药品分类：降血压药、抗心力衰竭药药物基本信息分类：第三代非选择性β肾上腺素受体阻滞剂（β1/β2无差别拮抗），同时选择性抑制α1肾上腺素受体，兼具双重受体拮抗活性。剂型：片剂（6.25 mg、10mg、12.5 mg、25 ...

SOUTH SAN FRANCISCO, Calif., March 17, 2025 (GLOBE NEWSWIRE) -- Cytokinetics, Incorporated (Nasdaq: CYTK) today announced five presentations related to aficamten, an investigational cardiac myosin ...

Dr Ghosh is preparing for human trials and is planning to collaborate with a government hospital in the city. Dr Ghosh further explained that in both cancer and normal cells, CYP1A and CYP2C9 proteins ...

氢氯噻嗪可造成光敏性皮疹、青苔样反应和红斑狼疮。 厄贝沙坦主要由CYP2C9代谢，同功酶CYP3A4几乎没有效应，因此极少发生相互作用。 噻嗪类利尿剂能降低钙的分泌，增加血钙水平。如果必须使用补钙剂、维生素D合用，应监测血清钙水平，必要时调整补钙剂 ...

There are drugs that enhance the effects of marijuana and THC. THC is metabolized by the CYP3A4 and CYP2C9 cytochromes, which are specialized proteins in the liver that detoxify drugs and toxins.

瑞舒伐他汀则主要经CYP2C9和CYP2C19代谢，与这些酶的抑制剂或诱导剂联用时需谨慎。辛伐他汀同样依赖CYP3A4代谢，使用时也要警惕药物相互作用。 普伐他汀不经细胞色素P450酶系代谢，主要经葡萄糖醛酸化途径代谢，这一特点使其与其他药物相互作用较少 ...

Introduction: Epilepsy patients with intellectual disability often suffer from drug-resistant epilepsy (DRE), which severely affects patients’ quality of life. Cenobamate (CNB) is a recently approved ...

The QSAR-based software ADMET Predictor 8.5 (Simulation Plus, Lancaster, CA, United States) was used to predict metabolic phenotyping for CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, ...