Additional data from the MDNA11 ABILITY-1 trial to be presented at the Annual Meeting TORONTO and HOUSTON, (GLOBE NEWSWIRE) -- Medicenna Therapeutics Corp. (“Medicenna” or the “Company”) (TSX: MDNA, ...

This study reports valuable findings on the role of Layilin in the motility and suppressive capacity of clonal expanded regulatory T cells (Tregs) in the skin. Although the strength of the study is ...

After just over a month of release, the Chinese mega-hit Ne Zha 2 has passed the $2 billion mark at the global box office. More precisely, it took just 33 days to achieve this unprecedented feat.

蓝鲸新闻2月24日讯（记者 王健文）聚焦自免赛道的三生国健（688336.SH ... 三生国健成立于2002年，2020年在上交所上市，彼时，公司的核心产品为益赛普（TNF-α抑制剂），另两款产品健尼哌（CD25单抗）、赛普汀（HER2靶向药物）也先后上市。 但在公司上市前夕 ...

Therapeutic depletion of immunosuppressive regulatory T cells (Treg) may overcome resistance to cancer immunotherapies. RG6292 is an anti-CD25 antibody that preferentially depletes Tregs while ...

For this, clinical, biochemical, metabolic, anthropometric and inflammatory aspects of each patient was considered. Results From the statistical analysis, a weakpositive correlation (r = 0.16) between ...

BMP4 is a key growth factor well known in promoting bone regeneration and has been reported to be able to regulate T cell development in the thymus. Here, we showed that BMP4 downregulates the ...

The IL-2/IL-2Ralpha (CD25) axis is of central importance for the interplay of effector and regulatory T cells. Nevertheless, the question how different antigen loads are translated into appropriate IL ...

In studies in murine models, active suppression by IL-10-secreting Foxp3 regulatory T cells (Tregs) has emerged as an essential mechanism in colon homeostasis. However, the role of the equivalent ...

The levels of total, naive and memory Tregs increased, mainly within the memory subset, but remained lower than healthy controls up to 2 years after transplantation. Reduced-intensity conditioning ...