此前研究发现，高血压的发生与多种因素相关，基因在其中起着重要作用，约 60% 的高血压风险变异可归因于遗传因素。MTHFR 基因编码的亚甲基四氢叶酸还原酶，对同型半胱氨酸（Hcy）和叶酸代谢至关重要。MTHFR C677T 多态性会使酶活性降低，导致 Hcy 水平升高，进而增加心血管疾病、中风等风险。然而，以往关于 MTHFR C677T 多态性、血清 Hcy 和高敏 C ...

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I had never heard of the MTHFR mutation until almost two years ago when I lost a second child to preterm labor. I wonder how many families can be spared the loss of their children by instituting a ...

It is well acknowledged that metabolic disorder binds closely with preeclampsia, though some of the causal relationships are still ambiguous. This review systematically summarizes the metabolic ...

ABSTRACT: Pulmonary embolism (PE) is defined as the sudden, partial or total obliteration of the pulmonary arteries or their branches by an embolus, most often fibrinocruoric. It plays a significant ...

为探究 MTHFR 基因多态性与早产（PTB）关系，研究人员分析 44 项研究，发现 C677T 多态性与 PTB 有关，A1298C 则无。 在生命的奇妙旅程中，新生命的诞生本是充满希望与喜悦的时刻，然而早产（Preterm Birth，PTB）却如同一朵阴霾，笼罩着无数家庭。PTB 指妊娠满 28 周至 ...

Background: The dysfunction of immune system and inflammation contribute to the Parkinson’s disease (PD) pathogenesis. Cytokines, oxidative stress, neurotoxin and metabolism associated enzymes ...

The incidence of chronic thromboembolic pulmonary hypertension is 6.5 per million person-years. 22 Applying these incidence rates to the 2000 US White population, approximately 1400 new chronic ...