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《Cell Death and Differentiation》染色体 3p 缺失与 8q 增益驱动脉络膜黑 ...
血管生成拟态的起源:VM 首次在 UM 细胞中被描述,研究人员对其起源进行了深入探究。他们发现 BAP1 基因(位于染色体 3p21.1)在 UM 患者中存在较高频率的突变,且与患者生存率降低相关。通过对 MUM 2B 和 MUM 2C 细胞系的研究发现,MUM 2B 细胞系具有与部分 UM 患者 ...
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