RNA-based therapeutics have rapidly emerged over the past decade, offering a new class of medicines that differ significantly from conventional drugs. These therapies can be programmed to target or ...

The emergence of '-omics' technologies capable of yielding deep molecular profiles of cancer genomes has enabled the elucidation of somatic genetic alterations associated with resistance to ...

Department of Chemistry, King’s College London, Britannia House, 7 Trinity Street, London SE1 1DB, U.K.

BOSTON, January 28, 2025--(BUSINESS WIRE)--Genialis, the RNA biomarker company, today announced an extension of its collaboration with Debiopharm, a Swiss-based global biopharmaceutical company ...

On the other hand, mechanisms of acquired resistance to 'pathway-targeted' drugs ... in the target receptor and mutations or gene amplification of compensatory receptors or other signaling ...

This cover highlights the article A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung diseasee by Kyungtae Lim, ...

Total RNA was isolated using TRIzol Reagent (Invitrogen ... In addition, as the dsRNA dose of 0.5 µg induced the same level of gene silencing as a 2 µg dose when the dsRNA + PEI complex was injected ...

In essence, it speeds up the amplification of RNA to produce a result in about 30 minutes, including the time to process samples before the test. The portable device can test up to four people at ...

Recent transcriptional profiling technologies are uncovering previously-undefined cell populations and molecular markers at an unprecedented pace. While single cell RNA (scRNA) sequencing is an ...

The dynamic structure of RNA plays a central role in post-transcriptional regulation of gene expression such as RNA maturation, degradation, and translation. With the rise of next-generation ...