“Writers” are methyltransferases, such as the NSUN family members and DNMT2, responsible for adding m5C methyl groups to RNA. “Erasers,” including demethylases like the TET family and ALKBH1, remove ...

研究人员针对子痫前期（PE）开展 ALKBH1 介导的 m 5 C 修饰研究，发现相关调控机制，为 PE 治疗提供新靶点。 子痫前期（Preeclampsia，PE）是一种严重影响母婴健康的妊娠期疾病，常常在孕妇妊娠 20 周后出现高血压、蛋白尿等症状。在中国，PE 的发病率约为 9.4% - 10.4 ...