Vascular remodeling in PAH is a complex and multifactorial process, but recent advances have identified several key genetic, cellular, and molecular abnormalities ... Macitentan is a dual ET-1 ...

Molecular Cancer Therapeutics publishes articles on the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug ...

The new structure incorporates chemical groups called sulfonates to make it compatible with water, allowing it to function in real-world water systems, like rivers or wastewater. It uses a natural ...

An artificial intelligence model has created a new protein that researchers say would have taken 500 million years to evolve in nature — if nature were capable of producing such a thing.

State Key Laboratory of Bioreactor Engineering East China University of Science and Technology 130 Meilong Road, Shanghai 200237, China Research Center for Systems Biosynthesis, China State Institute ...

Summary: Entrepreneurs often grapple with the decision of whether to structure their business as a Company or a Limited Liability Partnership (LLP). Both offer the advantage of limited liability and ...

The drug restored the cholinergic system and improved memory,” added Moreno. Rafael Rodríguez believes that “this molecule could become a drug to treat the symptoms of dementia, at least during the ...

Mice lacking BCL6 had 40% less muscle mass than their healthy counterparts, and the muscle they did have was compromised both in structure and function. However, when the researchers increased the ...

State Key Laboratory of Physical Chemistry of Solid Surfaces, College of Chemistry and Chemical Engineering, Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province ...

Molecular Cancer Research publishes articles featuring novel, basic cancer research discoveries that prioritize broad molecular and cellular processes. Areas of emphasis include cell cycle and ...