Dow Jones tracks 30 large U.S. companies, providing a snapshot of market health. Investors can't buy Dow stock but can invest via ETFs or shares of Dow companies. The Dow is price-weighted ...

THOUSANDS of drivers are set to face disruption as a major motorway bridge closes overnight for essential maintenance. The M4 Prince of Wales Bridge, a key connection over the River Severn, will ...

为探究干扰 UBE2L3 表达促进骨肉瘤细胞坏死性凋亡及影响其进程的机制，作者[第一作者单位] 研究人员开展相关研究。结果发现 UBE2L3 可调节 MLKL 表达促坏死，抑制骨肉瘤生长。推荐阅读，助您了解骨肉瘤治疗新靶点相关进展。 在医学研究的广阔领域中，有一种 ...

Necroptosis is a form of regulated necrosis that requires the activation of receptor-interacting kinase 3 (RIPK3 or RIP3) and its phosphorylation of the substrate MLKL (mixed lineage kinase ...

A pair of kinases, RIPK1 and RIPK3, as well as the RIPK3 substrate MLKL cause a form of programmed necrotic cell death in mammals termed necroptosis. We report here that male reproductive organs of ...