为探究 miR-34a-5p 在癫痫中的作用，研究人员开展相关研究，发现其或可调控 Wnt/β-catenin 通路，为癫痫治疗提供新靶点。 癫痫是一种极为常见的神经系统疾病，全球约有 5000 万人受其困扰。微小核糖核酸（MicroRNAs，miRNAs）是一类短链非编码 RNA，它能通过与靶基因 ...

为探究 miR-34a-5p 在多囊卵巢综合征（PCOS）中的作用，研究发现其可调节 Notch 信号通路影响颗粒细胞功能，为治疗提供新靶点。 多囊卵巢综合征（Polycystic Ovary Syndrome，PCOS）是一种让许多青春期和育龄女性烦恼不已的代谢内分泌疾病。全球范围内，大约 6% - 21% 的 ...

In the event of high heterogeneity, we conducted subgroup analyses stratified by individual members of the miR-34 family (miR-34a, miR-34b, and miR-34c) to explore potential sources of variability.

UFC and Bellator veteran Frank Mir’s comeback with the GFL has been put on hold. That’s because early Monday morning, Mir revealed on Instagram that he recently “underwent an emergency spinal fusion ...

透明质酸（HA）修饰氨基化的介孔二氧化硅纳米粒 叶酸（FA）-二乙胺乙基（DEAE）-聚乙二醇（PEG）修饰壳聚糖纳米粒 CD5抗体修饰负载编码嵌合抗原受体(CAR)的mRNA的LNP纳米粒 CD31抗体修饰负载mRNA的LNP纳米粒 CD117抗体修饰负载mRNA的LNP纳米粒 miR-34a和米铂（Cisplatin ...

MiR-146b has been identified as being overexpressed in human bladder cancer (BCa) and implicated in promoting cancer cell invasion. However, its specific involvement in BCa cell growth remains unclear ...

修饰负载miR-34a的支链聚乙烯亚胺（PEI） 通过两个Y形DNA单元和一个载有治疗性siRNA的双链DNA自组装而成的智能DNA纳米探针 通过酸敏感亚胺键将细胞穿透结构域（聚精氨酸）与聚阴离子屏蔽域连接并修饰负载PLK-1特异性siRNA和紫杉醇（PTX）的脂质体返回搜狐 ...

Frank Mir’s proposed Global Fight League debut is likely in jeopardy after he recently underwent emergency spinal surgery. Advertisement The Ultimate Fighting Championship and Bellator MMA ...

Mufti Shah Mir, Muslim scholar who helped Pakistan's ISI in abducting Kulbhushan Jadhav from Iran, shot dead by unknown men. Mufti Shah Mir was killed by unknown gunmen in Balochistan. Mir was ...

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Of these, miR-451 is the best characterized, and it contains a very small, distinctive loop structure. The preceding discussion of miRNA biogenesis should hint at the idea that miRNAs may play ...