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10 天
综述:ZEB1 和 ZEB2 在肿瘤进展中的双重作用
这篇综述探讨了 ZEB1 和 ZEB2 在肿瘤进展中的复杂作用,其影响因组织和癌症类型而异。 引言 上皮 - 间质转化(EMT)是一个可逆的生物学过程,上皮细胞在这个过程中失去细胞极性和细胞间黏附,获得间质表型。在胚胎发育、伤口愈合和组织稳态中,EMT 发挥着 ...
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