Aberrant expressions of matrix proteins by cancer-associated fibroblasts (CAFs) alter the mechanical properties of the tumor extracellular matrix (ECM). This results in increased ECM desmoplasia ...

Decellularization: The process of removing cells from a tissue or organ, leaving behind the ECM, which can be used as a scaffold for tissue engineering. Mesenchymal Stem Cells: A type of stem cell ...

Discover how Nobel laureate Ardem Patapoutian's research on PIEZO channels revolutionizes our understanding of human biology.

are specialized structures in the central nervous system (CNS) that play a crucial role in neuronal function and plasticity. These nets are composed of components from the extracellular matrix ...

This peptide, composed of three amino acids in a sequence engineered to emulate biological activity, might serve as a significant tool in understanding ECM biology, tissue remodeling, and cellular ...

The tumor microenvironment where malignant tissue grows is the external environment for the growth of tumor cells and tumor-associated cells. As an important component of the tumor microenvironment, ...

The nervous system is a central component of the human body, but most people don’t spend much time thinking about it. Amelia Chapman is a nervous system practitioner through her business ...

Researchers develop 3D blood-brain barrier model to study Alzheimers and neuroinflammation New platform created to improve ...

An international research team has discovered a new type of skeletal tissue that offers great ... Most cartilage relies on an external extracellular matrix for strength, but "lipocartilage ...

The nervous system is the body’s direct communication system. It’s made up of the body’s many nerve cells. These cells work together in a network that sends and receives signals from one ...

Jan. 28, 2025 — Investigators have identified in a preclinical model a specific brain circuit whose inhibition appears to reduce anxiety without side effects. Their work suggests a new target ...