综上所述，在生长因子受体激活条件下，ERK与USP9X共同参与了肝癌细胞中TK1表达的调控，通过同时增强其代谢与非代谢功能促进肿瘤的增殖。这一发现强调了TK1作为癌症治疗的潜在分子靶点，对靶向代谢酶的抗癌药物的研发具有重要的指导意义。

A recent study from Northwestern University has uncovered a genetic factor that may play a key role in autism. Researchers found that a specific gene affects how brain cells form connections during ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Glioblastoma multiforme (GBM) is the most ...

Breast cancer is the most prevalent malignancy among women worldwide. Despite significant advances in treatment, it remains one of the leading causes of female mortality. The inability to effectively ...

Introduction: Although age is the most important non-modifiable risk factor for cerebral stroke, it is also apparent that females commonly exhibit longer lifespan and better outcome after stroke ...

56 CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST); Universitat Pompeu Fabra (UPF), Barcelona, Spain 57 Unité de Neurophysiologie Clinique, Centre ...

7 The Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Glasgow, UK 8 Institute of Cancer Sciences, College of Medical, Veterinary and Life Sciences, University ...