腾讯网1 天
hLife编委风采 | 吕志民团队揭示胸苷激酶1促进肝癌细胞生长的重要机制
综上所述，在生长因子受体激活条件下，ERK与USP9X共同参与了肝癌细胞中TK1表达的调控，通过同时增强其代谢与非代谢功能促进肿瘤的增殖。这一发现强调了TK1作为癌症治疗的潜在分子靶点，对靶向代谢酶的抗癌药物的研发具有重要的指导意义。
The EMBO Journal4 天
Praja2 controls P-body assembly and translation in glioblastoma by non-proteolytic ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Glioblastoma multiforme (GBM) is the most ...